{"id":85,"date":"2019-07-16T21:11:31","date_gmt":"2019-07-16T18:11:31","guid":{"rendered":"https:\/\/treatment-diabetes-info.com\/blog\/?p=85"},"modified":"2019-07-16T21:15:46","modified_gmt":"2019-07-16T18:15:46","slug":"hereditary-pyropoikilocytosis","status":"publish","type":"post","link":"https:\/\/treatment-diabetes-info.com\/blog\/2019\/07\/16\/hereditary-pyropoikilocytosis\/","title":{"rendered":"Hereditary Pyropoikilocytosis"},"content":{"rendered":"<h2>What is Hereditary Pyropoikilocytosis?<\/h2>\n<p>This is a rare hereditary hemolytic anemia associated with impaired protein structure of the erythrocyte membrane; it is accompanied by severe intracellular destruction of red blood cells and low resistance of red blood cells to temperature changes.<\/p>\n<h2>Symptoms of Hereditary Pyropoikilocytosis<\/h2>\n<p>In children suffering from this disease, from an early age there is a sharp yellowness, a significant increase in the size of the spleen, as well as the liver.<\/p>\n<h2>Diagnosis of Hereditary Pyropoikilocytosis<\/h2>\n<p>The hemoglobin content is reduced to 5055 g \/ l, the content of reticulocytes is increased to 30%. Microspherocytes, pronounced anisocytosis, poikilocytosis, erythrocyte fragmentation, a significant number of erythrocaryocytes are observed in blood smears. The disease causes the increased sensitivity of erythrocytes to slight heating: erythrocytes are sharply deformed, severe fragmentation, poikilocytosis appear. Normally, such deformation occurs at 51-52 \u00b0 C. In pyropoikilocytosis, erythrocytes exhibit an unusually high concentration of calcium ions as a result of their increased penetration into the cell and delayed elimination.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>What is Hereditary Pyropoikilocytosis? This is a rare hereditary hemolytic anemia associated with impaired protein structure of the erythrocyte membrane; it is accompanied by severe intracellular destruction of red blood cells and low resistance of<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"closed","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"footnotes":""},"categories":[1],"tags":[],"_links":{"self":[{"href":"https:\/\/treatment-diabetes-info.com\/blog\/wp-json\/wp\/v2\/posts\/85"}],"collection":[{"href":"https:\/\/treatment-diabetes-info.com\/blog\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/treatment-diabetes-info.com\/blog\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/treatment-diabetes-info.com\/blog\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/treatment-diabetes-info.com\/blog\/wp-json\/wp\/v2\/comments?post=85"}],"version-history":[{"count":1,"href":"https:\/\/treatment-diabetes-info.com\/blog\/wp-json\/wp\/v2\/posts\/85\/revisions"}],"predecessor-version":[{"id":86,"href":"https:\/\/treatment-diabetes-info.com\/blog\/wp-json\/wp\/v2\/posts\/85\/revisions\/86"}],"wp:attachment":[{"href":"https:\/\/treatment-diabetes-info.com\/blog\/wp-json\/wp\/v2\/media?parent=85"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/treatment-diabetes-info.com\/blog\/wp-json\/wp\/v2\/categories?post=85"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/treatment-diabetes-info.com\/blog\/wp-json\/wp\/v2\/tags?post=85"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}